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Meloxicam CAS#71125-38-7

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Chemical Name:Meloxicam

CAS No.71125-38-7

Molecular Formula：C14H13N3O4S2

Molecular weight:351.4

Sample: Available

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Product Details

Products Description of Meloxicam CAS#71125-38-7

Meloxicam is a non-steroidal antipyretic, analgesic and anti-inflammatory drug. It is not a hormone drug. It has strong anti-inflammatory, analgesic and antipyretic effects. It can selectively inhibit the activity of cyclooxygenase-2 (COX-2), thereby blocking the synthesis of prostaglandins. Its inhibitory effect on the biosynthesis of prostaglandins in inflammatory sites is stronger than that on the biosynthesis of prostaglandins in the gastric mucosa or kidneys. It is safer than other NSAIDs. It is mainly used to relieve the symptoms of osteoarthritis, painful osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

Meloxicam Chemical Properties

Melting point	255 °C
density	1.613±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: soluble
form	Off-white solid
pka	4.08 in water; 4.24 ± 0.01 in water/ethanol (1:1); 4.63 ± 0.03 in water/ethanol (1:4)
color	yellow
Water Solubility	practically insoluble in water(0.154 mg/mL), with higher solubility observed in strong acids and bases.
Merck	14,5826
BCS Class	2(CLogP), 4 (LogP)
Stability:	Stable. Incompatible with strong oxidizing agents.
InChI	InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)
InChIKey	ZRVUJXDFFKFLMG-UHFFFAOYSA-N
SMILES	S1(=O)(=O)C2=CC=CC=C2C(O)=C(C(NC2=NC=C(C)S2)=O)N1C
EPA Substance Registry System	2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-, 1,1-dioxide (71125-38-7)

Safety Information

Hazard Codes	Xn,T
Risk Statements	22-36/37/38-25
Safety Statements	26-45-60-36/37
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	DL0702000
HazardClass	6.1
PackingGroup	III
HS Code	29349990
Hazardous Substances Data	71125-38-7(Hazardous Substances Data)
Toxicity	LD50 orally in mice: 470 mg/kg (Trummlitz, 1980)