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6-Methyluracil CAS#626-48-2

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Chemical Name：6-Methyluracil

CAS No.:626-48-2

Molecular Formula：C5H6N2O2

Molecular weight:126.11

Sample: Available

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Product Details

Products Description of 6-Methyluracil CAS#626-48-2

6-Methyluracil is a colorless crystal. The melting point is 311-312℃, and it has also been reported to be 270-280℃ (decomposition). It is soluble in water, hot ethanol and alkaline solution, and slightly soluble in ether. The pH value of the aqueous solution is 13.

6-Methyluracil Chemical Properties

Melting point	318 °C (dec.)(lit.)
density	1.226±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form	Fine Crystalline Powder
pka	pK1:9.52 (25°C)
color	White to almost white
Water Solubility	7 g/L (22 ºC)
Merck	14,6133
BRN	115647
InChIKey	SHVCSCWHWMSGTE-UHFFFAOYSA-N
CAS DataBase Reference	626-48-2(CAS DataBase Reference)
NIST Chemistry Reference	6-Methyluracil(626-48-2)
EPA Substance Registry System	2,4(1H,3H)-Pyrimidinedione, 6-methyl- (626-48-2)

Safety Information

Hazard Codes	Xn
Risk Statements	62-63
Safety Statements	36/37/39-45-36/37
RIDADR	1759
WGK Germany	3
RTECS	YR0700000
TSCA	Yes
HazardClass	8
PackingGroup	II
HS Code	29335995
Hazardous Substances Data	626-48-2(Hazardous Substances Data)
Toxicity	LD50 oral in rat: 64500mg/kg

Product Application of 6-Methyluracil CAS#626-48-2

2,4-Dihydroxy-6-methylpyrimidine, also known as 6-methyluracil, can be used to synthesize the cardiovascular drug dipyridamole (2,6-bis(diethanolamine)4,8-dipiperidinyl-pyrimidine-[5,4-d]pyrimidine). Dipyridamole was previously used to treat coronary artery insufficiency, angina pectoris, and prevent myocardial infarction. Currently, it is mainly used as an antithrombotic drug in heart surgery or valve replacement to reduce the formation of thromboembolism. It can also be used to synthesize orotic acid and the pesticide sildenafil. It is an important pharmaceutical and pesticide intermediate.

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