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6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID CAS#14714-24-0

6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID CAS#14714-24-0 Promotion Season Now in Store and Free Sample for Testing with Factory Price

Chemical Name:6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID

CAS No.:14714-24-0

Molecular Formula:C7H4ClN3O2

Molecular weight:197.58

Sample:Available

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Product Details

Products Description of 6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID CAS#14714-24-0

6-Chloromidazo[1,2-B]pyridazine-2-carboxylic acid can be used to prepare compounds which can be used as active pharmaceutical substances, in particular Trk antagonists, i.e. they block the intracellular kinase activity of Trk, e.g. TrkA (NGF) receptors. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophic factors. Trks play an important role in pain perception and in tumor cell growth and survival signaling. Therefore, Trk receptor kinase inhibitors may provide targeted treatments for conditions such as pain and cancer.

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6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID Chemical Properties

Melting point	248 °C
density	1.75±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMF, DMSO
form	Solid
pka	4.21±0.30(Predicted)
color	Beige
CAS DataBase Reference	14714-24-0(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38-43
Safety Statements	26-36/37/39-36/37
HazardClass	IRRITANT
HS Code	2933998090
Hazard Codes	Xi
Risk Statements	36/37/38-43
Safety Statements	26-36/37/39-36/37