Propiconazole CAS#60207-90-1

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Chemical Name:Propiconazole

CAS No.:60207-90-1

Molecular Formula:C15H17Cl2N3O2

Molecular weight:342.22

Sample: Available

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Product Details

Products Description of Propiconazole CAS#60207-90-1
he triazole compound propiconazole (Pcz), 1-[[2-(2,4- dichlorophenyl)-4-propyl-1, 3-dioxolan-2-yl]methyl]-1,2,4-triazole, is a kind of triazole fungicide (Fig. 1). It is used extensively in a variety of applications. It is used on grasses grown for seed, mushrooms, corn, wild rice, peanuts, almonds, sorghum, oats, pecans, apricots, peaches, nectarines, plums and prunes. On cereals it controls diseases caused by Erysiphe graminis, Leptosphaeria nodorum, Pseudocerosporella herpotrichoides, Puccinia spp., Pyrenophora teres, Rhynchosporium secalis, and Septoria spp.
Wheat crops are among the commodities most heavily treated with fungicides in the United States, and propiconazole comprises approximately 90% of this application. Propiconazole is soluble in water at a concentration of 110 mg/L, and concentrations as high as 24 mg/L have been reported in waters receiving runoff from agricultural endeavors using the fungicide.
It can act as a potent inhibitor of BR biosynthesis as has been found that it has inhibitory effect on hypocotyl elongation of cress plants (Lepidium sativum). This inhibitory effect of Pcz was reversed by co-application with brassinolide. Based on the Pcz structure additional BR inhibitors, such as 2RS, 4RS-1-[2-(4- trifluoromethylphenyl)-4-n-propyl-1, 3-dioxolan-2-ylmethyl]-1H- 1,2,4-triazole, were identified. On the other hand, Pcz has been commercially used as fungistat (BannerMaxx, Syngenta) against a broad range of phytopathogenic fungi. Its fungistatic mode of action is the same as that of Ucz and Pac, blocking of lanosterol 14R-demethylase (CYP51A1). Pcz has also been studied extensively for its toxicity on plants, animals, humans, and the environment. Here we present a molecular genetic analysis of Pcz’s effects on Arabidopsis and maize seedlings.
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Propiconazole Chemical Properties

Melting point 

<25 °C

Boiling point 

180°C (0.1 torr)

density 

1.2700

vapor pressure 

5.6 x l0-5 Pa (25 °C)

refractive index 

1.6100 (estimate)

Fp 

11 °C

storage temp. 

APPROX 4°C

solubility 

DMF: 33 mg/ml,DMF:PBS (pH 7.2)(1:3): 0.16 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml

Water Solubility 

100 mg l-1(2O °C)

pka

2.94±0.12(Predicted)

form 

Oil

Specific Gravity

1.29 (20℃)

Merck 

13,7910

BRN 

9349305

Stability:

Stable. Incompatible with strong oxidizing agents.

InChIKey

STJLVHWMYQXCPB-UHFFFAOYSA-N

LogP

3.7 at 25℃

CAS DataBase Reference

60207-90-1(CAS DataBase Reference)

EPA Substance Registry System

Propiconazole (60207-90-1)


Safety Information

Hazard Codes 

Xn,N,T,F

Risk Statements 

22-43-50/53-39/23/24/25-23/24/25-11

Safety Statements 

36/37-46-60-61-45-16-7

RIDADR 

UN3082 9/PG 3

WGK Germany 

3

RTECS 

XZ4620000

HS Code 

29349990

Hazardous Substances Data

60207-90-1(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 1517 mg/kg (Urech)

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Inventory 2-3 working days New production 7-10 working days


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