Propiconazole CAS#60207-90-1
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Chemical Name:Propiconazole
CAS No.:60207-90-1
Molecular Formula:C15H17Cl2N3O2
Molecular weight:342.22
Sample: Available
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Products Description of Propiconazole CAS#60207-90-1
he triazole compound propiconazole (Pcz), 1-[[2-(2,4- dichlorophenyl)-4-propyl-1, 3-dioxolan-2-yl]methyl]-1,2,4-triazole, is a kind of triazole fungicide (Fig. 1). It is used extensively in a variety of applications. It is used on grasses grown for seed, mushrooms, corn, wild rice, peanuts, almonds, sorghum, oats, pecans, apricots, peaches, nectarines, plums and prunes. On cereals it controls diseases caused by Erysiphe graminis, Leptosphaeria nodorum, Pseudocerosporella herpotrichoides, Puccinia spp., Pyrenophora teres, Rhynchosporium secalis, and Septoria spp.
Wheat crops are among the commodities most heavily treated with fungicides in the United States, and propiconazole comprises approximately 90% of this application. Propiconazole is soluble in water at a concentration of 110 mg/L, and concentrations as high as 24 mg/L have been reported in waters receiving runoff from agricultural endeavors using the fungicide.
It can act as a potent inhibitor of BR biosynthesis as has been found that it has inhibitory effect on hypocotyl elongation of cress plants (Lepidium sativum). This inhibitory effect of Pcz was reversed by co-application with brassinolide. Based on the Pcz structure additional BR inhibitors, such as 2RS, 4RS-1-[2-(4- trifluoromethylphenyl)-4-n-propyl-1, 3-dioxolan-2-ylmethyl]-1H- 1,2,4-triazole, were identified. On the other hand, Pcz has been commercially used as fungistat (BannerMaxx, Syngenta) against a broad range of phytopathogenic fungi. Its fungistatic mode of action is the same as that of Ucz and Pac, blocking of lanosterol 14R-demethylase (CYP51A1). Pcz has also been studied extensively for its toxicity on plants, animals, humans, and the environment. Here we present a molecular genetic analysis of Pcz’s effects on Arabidopsis and maize seedlings.
Propiconazole Chemical Properties |
Melting point | <25 °C |
Boiling point | 180°C (0.1 torr) |
density | 1.2700 |
vapor pressure | 5.6 x l0-5 Pa (25 °C) |
refractive index | 1.6100 (estimate) |
Fp | 11 °C |
storage temp. | APPROX 4°C |
solubility | DMF: 33 mg/ml,DMF:PBS (pH 7.2)(1:3): 0.16 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml |
Water Solubility | 100 mg l-1(2O °C) |
pka | 2.94±0.12(Predicted) |
form | Oil |
Specific Gravity | 1.29 (20℃) |
Merck | 13,7910 |
BRN | 9349305 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | STJLVHWMYQXCPB-UHFFFAOYSA-N |
LogP | 3.7 at 25℃ |
CAS DataBase Reference | 60207-90-1(CAS DataBase Reference) |
EPA Substance Registry System | Propiconazole (60207-90-1) |
Safety Information |
Hazard Codes | Xn,N,T,F |
Risk Statements | 22-43-50/53-39/23/24/25-23/24/25-11 |
Safety Statements | 36/37-46-60-61-45-16-7 |
RIDADR | UN3082 9/PG 3 |
WGK Germany | 3 |
RTECS | XZ4620000 |
HS Code | 29349990 |
Hazardous Substances Data | 60207-90-1(Hazardous Substances Data) |
Toxicity | LD50 orally in rats: 1517 mg/kg (Urech) |
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