Guanidine Hydrochloride 99.5% CAS#50-01-1
Guanidine hydrochloride 99.5% CAS#50-01-1 Promotion Season Now in Store and Free Sample for Testing with Factory Price
Chemical Name:Guanidine hydrochloride 99.5%
CAS No.: 50-01-1
Molecular Formula: CH5N3.ClH
Molecular weight: 95.53
Sample: Available
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Products Description of Guanidinehydrochloride99.5% CAS#50-01-1
Guanidine hydrochloride, chemical name is carbamidine hydrochloride, is a white or slightly yellow block, almost insoluble in acetone, benzene and ether. It can be used as an intermediate for medicines, pesticides, dyes and other organic synthesis. It is an important raw material for the manufacture of sulfadiazine, sulfamethylpyrimidine, sulfadimethylpyrimidine and other drugs and folic acid. It can also be used as an antistatic agent for synthetic fibers.
Product Parameters of Guanidinehydrochloride99.5%CAS#50-01-1
1.Names and Identifiers
Name | Guanidine hydrochloride |
Synonyms
| 1-methylguanidine hydrochloride Amino(imino)methanaminium chloride AMINOFORMAMIDINE HCL Aminoformamidine hydrochloride Aminoformamidine hydrochloride.Aminomethanamidine Aminoformamidine hydrochloride,Guanidinium chloride,Guanidium hydrochloride,Guanidinium chloride chloride Aminomethanamidine hydrochlorid Cough. EINECS 200-002-3 GdmCl Guanidine (hydrochloride) guanidine chlorhydrate Guanidine chloride Guanidine HCI Guanidine Hydrochlor Guanidine hydrochloride(1:1) Guanidine monohydrochloride Guanidine, hydrochloride(1:1) Guanidine, monohydrochloride Guanidinehydrochloride Guanidinhydrochlorid guanidinium chloride guanidinium hydrochloride GUANIDIUM CHLORIDE GUHY hydrochloric acid guanidine MFCD00013026 Redness. Redness.Pain. usafek-749 ZYZUM &&HCI
|
CAS
| No. 50-01-1 |
CID | 5742 |
EINECS(EC#) | 200-002-3 |
Molecular Formula | CH6ClN3 (isomer) |
Inchi | InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
|
InChIkey
| PJJJBBJSCAKJQF-UHFFFAOYSA-N
|
Canonical Smiles
| C(=N)(N)N.Cl
|
Isomers Smiles
| C(=N)(N)N.Cl
|
2. Properties
Density
| 1.18 g/mL at 25 °C(lit.)
|
Melting point
| 180-185 °C(lit.)
|
Boiling point | 132.9 °C at 760 mmHg
|
Refractive index | n20/D 1.465
|
Flash Point
| 34.2 °C
|
Precise Quality
| 95.02500
|
PSA
| 75.89000 |
logP
| 1.14090
|
Solubility | H2O: 6?M, clear, colorless
|
Appearance
| DryPowder; DryPowder, Liquid
|
Storage | Store at RT.
|
Chemical Properties
| White cryst. powder
|
Color/Form
| White to slightly yellow
|
Odo | Odorless |
PH | 4.5-5.5 (100g/l, H2O, 20℃)
|
Water Solubility
| H2O: 2280 g/L (20 oC)
|
Stability | Stable. Hygroscopic. Incompatible with strong oxidizing agents.
|
StorageTemp | Store at RT. |
3. Use and Manufacturing
3.1 Definition
ChEBI: An aminocarboxamidine, the parent compound of the guanidines.
3.2 Purification Methods
Crystallise the hydrochloride from hot methanol by chilling to about -10o, with vigorous stirring. The fine crystals are filtered through fritted glass, washed with cold (-10o) methanol, dried at 50o under vacuum for 5hours. (The product is purer than that obtained by crystallisation at room temperature from methanol by adding large amounts of diethyl ether.) [Kolthoff et al. J Am Chem Soc 79 5102 1957, Beilstein 3 H 86, 3 II 71, 3 III 160, 3 IV 150.] Guanidine hydrochloride Preparation Products And Raw materials Preparation Products
3.3 Usage
Guanidine hydrochloride is used in RNA isolation to dissociate nucleoproteins and inhibit RNase. Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Product Application of Guanidinehydrochloride 99.5%CAS#50-01-1
· Can be used as pharmaceuticals, pesticides, dyes and other organic synthesis intermediates
· Can be used to synthesize 2-aminopyrimidine, 2-amino-6-methylpyrimidine, 2-amino-4,6-dimethylpyrimidine It is an intermediate for the manufacture of sulfa drugs such as sulfadiazine, sulfamethylpyrimidine, and sulfamethamine.
· Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to form 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize the anti-anemia drug folic acid. It can also be used as an antistatic agent for synthetic fibers.
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