(-)-(R)-Mandelic Acid CAS#611-71-2
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Chemical Name:(-)-(R)-Mandelic Acid
CAS No.:611-71-2
Molecular Formula:C8H8O3
Molecular weight:152.15
Sample: Available
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Products Description of (-)-(R)-Mandelic Acid CAS#611-71-2
D-mandelic acid is a polar molecule. Because it contains hydroxyl and carboxyl groups, the molecule has a certain degree of hydrophilicity. Since D-mandelic acid is a chiral molecule, its physical and chemical properties are affected by the stereostructure of its molecule. In addition, the acid-base properties of D-mandelic acid are also affected by the molecular structure. The acidity of its carboxyl group is weak because the hydroxyl group on the chiral carbon atom replaces a hydrogen atom, which reduces the resonance stability of the negative charge. From the perspective of chemical reactions, the chiral structure of D-mandelic acid also affects the chirality of its reaction products. This chiral property is of great significance in organic synthesis and can be used to prepare drugs and chemicals of chiral molecules.
Mandelic acid Chemical Properties
Melting point | 131-133 °C(lit.) |
-150 º (c=2.5, H2O) | |
Boiling point | 214.6°C (rough estimate) |
density | 1.1677 (rough estimate) |
refractive index | -153.5 ° (C=1, H2O) |
Fp | >190℃ |
storage temp. | Store below +30°C. |
solubility | 109.8g/l soluble |
form | Crystalline Powder, Crystals or Flakes |
pka | 3.37(at 25℃) |
color | White to slightly yellow-beige |
PH | 3.34(1 mM solution);2.75(10 mM solution);2.22(100 mM solution); |
optical activity | [α]25/D 151°, c = 1 in ethanol |
Water Solubility | It is partly soluble in water, freely soluble in isopropyl and ethyl alcohol. |
Sensitive | Light Sensitive |
BRN | 2691094 |
Stability: | Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents. |
InChIKey | IWYDHOAUDWTVEP-SSDOTTSWSA-N |
LogP | 0.550 (est) |
CAS DataBase Reference | 611-71-2(CAS DataBase Reference) |
EPA Substance Registry System | Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)- (611-71-2) |
Safety Information
Hazard Codes | Xi |
Risk Statements | 41-36/37/38 |
Safety Statements | 22-24/25-36-26-39-37/39 |
WGK Germany | 1 |
Hazard Note | Irritant/Light Sensitive |
TSCA | Yes |
HS Code | 29181980 |
Toxicity | LD50 orally in Rabbit: 5000 mg/kg |
Product Application of (-)-(R)-Mandelic Acid CAS#611-71-2
A chiral resolving agent used in organic synthesis and the pharmaceutical industry, as a reagent for analyzing bases, analyzing alcohols via esters, and analyzing α-alkylation via stereoselective dioxolane
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