Lidocaine CAS#137-58-6

Products Description of Lidocaine CAS#137-58-6

Lidocaine exerts its local anesthetic effect by reversibly blocking sodium channels and blocking the transmission of action potentials on nerve fibers. Sensory nerve fibers are blocked earlier than motor nerve fibers, so low doses of lidocaine can exert selective sensory blocking effects. Lidocaine also has antiarrhythmic effects and belongs to Class Ib antiarrhythmic drugs. It can reduce ventricular rate, shorten action potential time and absolute refractory period, and prolong relative refractory period. Lidocaine has a rapid onset and a short duration. Adding epinephrine to lidocaine can reduce the rate of systemic absorption, thereby prolonging the duration of anesthesia.

Lidocaine Chemical Properties

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Product Application of Lidocaine CAS#137-58-6

Lidocaine is the first-line drug for the treatment of ventricular arrhythmias caused by acute and severe hemodynamic abnormalities. It is also effective for some supraventricular arrhythmias, such as supraventricular tachycardia mediated by the bypass and cardioversion of acute onset or parasympathetic-mediated atrial fibrillation. It is widely used for surface anesthesia of mucous membranes (such as before endotracheal intubation). EMLA cream is used for surface anesthesia of the skin before intravenous cannulation. To ensure the anesthetic effect, it needs to be applied to the skin for 45 to 60 minutes, and wrapped with an airtight dressing to promote absorption. EMLA is very useful for rabbit ear vein cannulation and intravenous cannulation of young dogs and cats.

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