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2-Hydroxypropyl-β-cyclodextrinCAS#128446-35-5

2-Hydroxypropyl-β-cyclodextrin CAS#128446-35-5 Promotion Season Now in Store and Free Sample for Testing with Factory Price

Chemical Name：2-Hydroxypropyl-β-cyclodextrin

CAS No.:128446-35-5

Molecular Formula：C63H112O42

Molecular weight:1541.54

Sample: Available

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Product Details

Products Description of 2-Hydroxypropyl-β-cyclodextrinCAS#128446-35-5

Hydroxypropyl-BETA-cyclodextrin is one of the most intensively studied and widely used cyclodextrin derivatives. It is mainly used in the food, medicine and cosmetics industries.

2-Hydroxypropyl-β-cyclodextrin Chemical Properties

Melting point	278 °C (dec.)
Boiling point	400℃
density	1.05 at 20.3℃
refractive index	125 ° (C=1, H2O)
storage temp.	room temp
solubility	H2O: 45 % (w/v)
form	solution (clear, colorless)
color	White to slightly yellow
optical activity	[α]26/D +139°, c = 1 in H2O
Water Solubility	Soluble in water.
InChIKey	ODLHGICHYURWBS-FOSILIAISA-N
LogP	-4 at 20℃
Surface tension	63.6-65mN/m at 1g/L and 22℃
EPA Substance Registry System	.BETA.-Cyclodextrin, 2-hydroxypropyl ethers (128446-35-5)

Safety Information

Safety Statements	24/25
WGK Germany	3
RTECS	GU2293332
TSCA	Yes
HS Code	29400090
Toxicity	mouse,LD,intravenous,> 5gm/kg (5000mg/kg),Journal of Pharmaceutical Sciences. Vol. 84, Pg. 1223, 1995.

Product Application of 2-Hydroxypropyl-β-cyclodextrin CAS#128446-35-5

Hydroxypropyl-BETA-cyclodextrin is an ideal injection solubilizer and drug excipient. It can improve the water solubility of poorly soluble drugs, increase drug stability, improve drug bioavailability, increase the efficacy of drugs or reduce the dosage, adjust or control the release rate of drugs, and reduce drug toxicity and side effects.

1. In the field of food and spices, it can improve the stability and long-term effect of nutrient molecules, cover or correct the bad smell and taste of food nutrient molecules, and improve production processes and product quality. The product has good solubility in water, and can be miscible with water in any proportion with a substitution degree of 4 or above, and can also be dissolved in 50% ethanol and methanol.

2. It is used as a stabilizer, emulsifier, deodorant, etc. in cosmetic raw materials to reduce the irritation of organic molecules in cosmetics to skin and mucous membrane tissues, enhance the stability of active ingredients, and prevent the volatilization and oxidation of nutrients. It has a certain relative hygroscopicity.

3. In the pharmaceutical industry, it is an ideal injection solubilizer and drug excipient because of its relatively low relative surface activity and hemolytic activity and no irritation to muscles.

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