1-Methylpiperazine CAS#109-01-3

1-Methylpiperazine CAS#109-01-3 Promotion Season Now in Store and Free Sample for Testing with Factory Price

Chemical Name:1-Methylpiperazine

CAS No.109-01-3

Molecular Formula:C5H12N2

Molecular weight: 100.16

Sample: Available

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Product Details

Products Description of 1-Methylpiperazine CAS#109-01-3

Colorless liquid. Boiling point 138℃ (140℃), relative density 0.903 (20/4℃), refractive index 1.4378, flash point 42℃, soluble in water, ether, ethanol, miscible with water, methanol, etc. in any ratio, weakly alkaline in aqueous solution.



1-Methylpiperazine Chemical Properties

Melting point 

-6 °C

Boiling point 

138 °C(lit.)

density 

0.903 g/mL at 25 °C(lit.)

vapor density 

3.5 (vs air)

vapor pressure 

12 hPa (20 °C)

refractive index 

n20/D 1.466(lit.)

Fp 

108 °F

storage temp. 

2-8°C

solubility 

Chloroform (Soluble), Methanol (Soluble)

pka

pK1:4.94(+2);pK2:9.09(+1) (25°C,μ=0.1)

form 

Liquid

color 

Clear

Specific Gravity

0.903

PH

11-12 (50g/l, H2O, 20℃)

explosive limit

1.2-9.9%(V)

Water Solubility 

soluble

Sensitive 

Hygroscopic

BRN 

102724

InChIKey

PVOAHINGSUIXLS-UHFFFAOYSA-N

LogP

-0.57 at 25℃

CAS DataBase Reference

109-01-3(CAS DataBase Reference)

NIST Chemistry Reference

Piperazine, 1-methyl-(109-01-3)

EPA Substance Registry System

Piperazine, 1-methyl- (109-01-3)

Safety Information

Hazard Codes 

T,F,C,Xi

Risk Statements 

10-21-23-34-36/37/38-20/21

Safety Statements 

16-26-36/37/39-45-36

RIDADR 

UN 2734 8/PG 2

WGK Germany 

2

RTECS 

TM1225000

Autoignition Temperature

320 °C

Hazard Note 

Flammable/Toxic/Corrosive/Store under nitrogen

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29335995

Toxicity

LD50 orally in Rabbit: 2547 mg/kg LD50 dermal Rabbit 1341 mg/kg


Product Application of 1-Methylpiperazine CAS#109-01-3

Organic synthesis intermediate. In the pharmaceutical industry, it is used to prepare antibiotics such as mepiramycin and antipsychotics such as trifluoperazine. It is mainly used as an intermediate for drugs such as ofloxacin, clozapine, sildenafil, toloxacin, zopiclone, etc. It can also be used in pesticides, dyes, plastics and other industries.

Synthesizes dozens of drugs such as nifuroxil (also known as furanpiperazineamide, Nifurpipone) and trifluoperazine

Intermediates for organic synthesis, pharmaceuticals, synthetic fibers, etc.

Used to prepare antibiotics such as mepiramycin, antipsychotics such as trifluoperazine and ofloxacin, etc.


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