1-Methylpiperazine CAS#109-01-3
1-Methylpiperazine CAS#109-01-3 Promotion Season Now in Store and Free Sample for Testing with Factory Price
Chemical Name:1-Methylpiperazine
CAS No.109-01-3
Molecular Formula:C5H12N2
Molecular weight: 100.16
Sample: Available
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Products Description of 1-Methylpiperazine CAS#109-01-3
Colorless liquid. Boiling point 138℃ (140℃), relative density 0.903 (20/4℃), refractive index 1.4378, flash point 42℃, soluble in water, ether, ethanol, miscible with water, methanol, etc. in any ratio, weakly alkaline in aqueous solution.
1-Methylpiperazine Chemical Properties
Melting point | -6 °C |
Boiling point | 138 °C(lit.) |
density | 0.903 g/mL at 25 °C(lit.) |
vapor density | 3.5 (vs air) |
vapor pressure | 12 hPa (20 °C) |
refractive index | n20/D 1.466(lit.) |
Fp | 108 °F |
storage temp. | 2-8°C |
solubility | Chloroform (Soluble), Methanol (Soluble) |
pka | pK1:4.94(+2);pK2:9.09(+1) (25°C,μ=0.1) |
form | Liquid |
color | Clear |
Specific Gravity | 0.903 |
PH | 11-12 (50g/l, H2O, 20℃) |
explosive limit | 1.2-9.9%(V) |
Water Solubility | soluble |
Sensitive | Hygroscopic |
BRN | 102724 |
InChIKey | PVOAHINGSUIXLS-UHFFFAOYSA-N |
LogP | -0.57 at 25℃ |
CAS DataBase Reference | 109-01-3(CAS DataBase Reference) |
NIST Chemistry Reference | Piperazine, 1-methyl-(109-01-3) |
EPA Substance Registry System | Piperazine, 1-methyl- (109-01-3) |
Safety Information
Hazard Codes | T,F,C,Xi |
Risk Statements | 10-21-23-34-36/37/38-20/21 |
Safety Statements | 16-26-36/37/39-45-36 |
RIDADR | UN 2734 8/PG 2 |
WGK Germany | 2 |
RTECS | TM1225000 |
Autoignition Temperature | 320 °C |
Hazard Note | Flammable/Toxic/Corrosive/Store under nitrogen |
TSCA | Yes |
HazardClass | 3 |
PackingGroup | III |
HS Code | 29335995 |
Toxicity | LD50 orally in Rabbit: 2547 mg/kg LD50 dermal Rabbit 1341 mg/kg |
Product Application of 1-Methylpiperazine CAS#109-01-3
Organic synthesis intermediate. In the pharmaceutical industry, it is used to prepare antibiotics such as mepiramycin and antipsychotics such as trifluoperazine. It is mainly used as an intermediate for drugs such as ofloxacin, clozapine, sildenafil, toloxacin, zopiclone, etc. It can also be used in pesticides, dyes, plastics and other industries.
Synthesizes dozens of drugs such as nifuroxil (also known as furanpiperazineamide, Nifurpipone) and trifluoperazine
Intermediates for organic synthesis, pharmaceuticals, synthetic fibers, etc.
Used to prepare antibiotics such as mepiramycin, antipsychotics such as trifluoperazine and ofloxacin, etc.
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