Terbinafine CAS#91161-71-6

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Chemical Name:Terbinafine

CAS No.:91161-71-6

Molecular Formula:C21H25N

Molecular weight:291.43

Sample: Available

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Product Details

Products Description of Terbinafine CAS#91161-71-6 

Terbinafine hydrochloride can treat skin, hair and nail infections caused by Trichophyton, Microsporum canis and Epidermophyton floccosum. It can also treat various tinea, skin yeast infections caused by Candida, and onychomycosis caused by mold. Terbinafine hydrochloride is an allylamine antifungal drug that inhibits squalene epoxidase in the synthesis of ergosterol in fungal cells and causes squalene to accumulate in cells, thereby killing bacteria.



Terbinafine Chemical Properties

Melting point 

203-205 °C

Boiling point 

417.9±33.0 °C(Predicted)

density 

1.007±0.06 g/cm3(Predicted)

vapor pressure 

0Pa at 25℃

storage temp. 

2-8°C

solubility 

soluble in Methanol

form 

powder to crystal

pka

6.92±0.50(Predicted)

color 

White to Light yellow

LogP

3.3 at 37℃ and pH7

CAS DataBase Reference

91161-71-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

HS Code 

2921450090


Product Application of Terbinafine CAS#91161-71-6 

Allylamine antifungal drugs have a wider antibacterial spectrum than naftifine and higher antifungal activity. They can highly selectively inhibit the squalene epoxidase of fungi, which blocks the squalene epoxidation reaction during the formation of fungal cell membranes and destroys the formation of chemical books in fungal cell membranes, thereby killing or inhibiting fungi. They are safe, low in toxicity, have few side effects, are well tolerated for oral and topical use, and have no teratogenicity or embryotoxicity. They are clinically used for various skin fungal infections (tinea pedis, tinea cruris, and tinea corporis) and nail fungal infections.


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