Diethyl Ethoxymethylenemalonate CAS#87-13-8

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Chemical Name:Diethyl Ethoxymethylenemalonate

CAS No.:87-13-8

Molecular Formula:C10H16O5

Molecular weight:216.23

Sample: Available

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Product Details

Products Description of Diethyl Ethoxymethylenemalonate CAS#87-13-8

Ethoxymethylene, also known as diethyl ethoxymethylenemalonate, is a colorless, transparent and viscous liquid. It is an important pharmaceutical intermediate and is widely used in the synthesis of medicines, pesticides and auxiliaries. It is used in the production of chloroquine, Intermediates of norfloxacin and lomefloxacin.




Diethyl ethoxymethylenemalonate Chemical Properties

Melting point 

-33°C

Boiling point 

279-283 °C(lit.)

density 

1.080 g/mL at 20 °C(lit.)

vapor pressure 

<0.1 hPa

refractive index 

n20/D 1.463

Fp 

311 °F

storage temp. 

Store below +30°C.

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Liquid

color 

Clear colorless to light yellow

Water Solubility 

insoluble

BRN 

880058

InChIKey

LTMHNWPUDSTBKD-UHFFFAOYSA-N

LogP

1.5-2.1 at pH7

CAS DataBase Reference

87-13-8(CAS DataBase Reference)

NIST Chemistry Reference

Propanedioic acid, (ethoxymethylene)-, diethyl ester(87-13-8)

EPA Substance Registry System

Propanedioic acid, (ethoxymethylene)-, diethyl ester (87-13-8)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38-42/43

Safety Statements 

26-36/37/39-27-24/25

WGK Germany 

1

RTECS 

OO1100000

Autoignition Temperature

215 °C

TSCA 

Yes

HS Code 

29189090

Toxicity

LD50 orally in Rabbit: 925 mg/kg LD50 dermal Rat > 2000 mg/kg


Product Application of Diethyl Ethoxymethylenemalonate CAS#87-13-8

An important organic raw material containing a variety of active groups in the molecule, which can perform polycondensation and cyclization condensation with a variety of substances. It is now mainly used to synthesize norfloxacin.


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