Diethyl Ethoxymethylenemalonate CAS#87-13-8
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Chemical Name:Diethyl Ethoxymethylenemalonate
CAS No.:87-13-8
Molecular Formula:C10H16O5
Molecular weight:216.23
Sample: Available
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Products Description of Diethyl Ethoxymethylenemalonate CAS#87-13-8
Ethoxymethylene, also known as diethyl ethoxymethylenemalonate, is a colorless, transparent and viscous liquid. It is an important pharmaceutical intermediate and is widely used in the synthesis of medicines, pesticides and auxiliaries. It is used in the production of chloroquine, Intermediates of norfloxacin and lomefloxacin.
Diethyl ethoxymethylenemalonate Chemical Properties
Melting point | -33°C |
Boiling point | 279-283 °C(lit.) |
density | 1.080 g/mL at 20 °C(lit.) |
vapor pressure | <0.1 hPa |
refractive index | n20/D 1.463 |
Fp | 311 °F |
storage temp. | Store below +30°C. |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
form | Liquid |
color | Clear colorless to light yellow |
Water Solubility | insoluble |
BRN | 880058 |
InChIKey | LTMHNWPUDSTBKD-UHFFFAOYSA-N |
LogP | 1.5-2.1 at pH7 |
CAS DataBase Reference | 87-13-8(CAS DataBase Reference) |
NIST Chemistry Reference | Propanedioic acid, (ethoxymethylene)-, diethyl ester(87-13-8) |
EPA Substance Registry System | Propanedioic acid, (ethoxymethylene)-, diethyl ester (87-13-8) |
Safety Information
Hazard Codes | Xn |
Risk Statements | 22-36/37/38-42/43 |
Safety Statements | 26-36/37/39-27-24/25 |
WGK Germany | 1 |
RTECS | OO1100000 |
Autoignition Temperature | 215 °C |
TSCA | Yes |
HS Code | 29189090 |
Toxicity | LD50 orally in Rabbit: 925 mg/kg LD50 dermal Rat > 2000 mg/kg |
Product Application of Diethyl Ethoxymethylenemalonate CAS#87-13-8
An important organic raw material containing a variety of active groups in the molecule, which can perform polycondensation and cyclization condensation with a variety of substances. It is now mainly used to synthesize norfloxacin.
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