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Glutathione CAS#70-18-8

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Chemical Name：Glutathione

CAS No.:70-18-8

Molecular Formula：C10H17N3O6S

Molecular weight:307.32

Sample: Available

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Product Details

Products Description of Glutathione CAS#70-18-8

Glutathione is a tripeptide compound formed by glutamic acid, cysteine and glycine through peptide bond condensation. It is the most important low-molecular thiol for anti-oxidative stress in mammalian cells. It was discovered in 1921 and its chemical structure was determined in 1930. Dr. Al Mindell, a famous American nutrition and health expert, called glutathione a triple-effective anti-aging amino acid. It is also known as nature's antioxidant master. It has the appearance of colorless, transparent, elongated granular crystals. It is soluble in water, dilute alcohol, liquid ammonia, dimethylformamide, and insoluble in ethanol, ether, and acetone. Its properties are stable when it is solid, and its aqueous solution is easily oxidized to oxidized glutathione in the air. It is widely present in baker's yeast, wheat germ, animal liver, chicken blood, pig blood, tomatoes, pineapples, and cucumbers. Among them, wheat germ and animal liver have the highest content, with a content of up to 100-1000 mg/100g. It has the functions of anti-oxidation, scavenging free radicals, detoxification, enhancing immunity, delaying aging, anti-cancer, and anti-radiation hazards. It also helps white blood cells kill bacteria, prevents oxidation of vitamins C and E, and prevents stroke and cataract formation. In addition, glutathione also has the function of binding carcinogens and excreting them out of the body through urine.

Glutathione Chemical Properties

Melting point	192-195 °C (dec.) (lit.)
alpha	-16.5 º (c=2, H2O)
Boiling point	754.5±60.0 °C(Predicted)
density	1.4482 (rough estimate)
refractive index	-17 ° (C=2, H2O)
storage temp.	2-8°C
solubility	H2O: 50 mg/mL
form	powder
pka	pK1 2.12; pK2 3.53; pK3 8.66; pK4 9.12(at 25℃)
color	White
PH	3 (10g/l, H2O, 20°C)
Odor	Odorless
Water Solubility	soluble
Merck	14,4475
BRN	1729812
Sequence	H-γ-Glu-Cys-Gly-OH
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	RWSXRVCMGQZWBV-WDSKDSINSA-N
LogP	-1.645 (est)
CAS DataBase Reference	70-18-8(CAS DataBase Reference)
EPA Substance Registry System	Glutathione (70-18-8)

Safety Information

Hazard Codes	Xi
Risk Statements	68-36/37/38
Safety Statements	24/25-36/37/39-27-26
WGK Germany	2
RTECS	MC0556000
F	9-23
TSCA	Yes
HS Code	29309070

Product Application of Glutathione CAS#70-18-8

Endogenous antioxidant that plays an important role in the reduction of reactive oxygen species formed during cellular metabolism and respiratory bursts. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules with electrophilic centers. Glutathione also forms disulfide bonds with cysteine residues in proteins. Through these mechanisms, it can have the paradoxical effect of reducing the effectiveness of anticancer agents.

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