Triethylamine CAS#121-44-8

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Chemical Name:Triethylamine

CAS No.121-44-8  

Molecular Formula:C6H15N

Molecular weight:101.19

Sample: Available

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Product Details

Products Description of Triethylamine CAS#121-44-8 

Triethylamine (molecular formula: C6H15N), also known as N,N-diethylethylamine, is the simplest homotrisubstituted tertiary amine. It has the typical properties of tertiary amines, including salt formation and oxidation. Triethylamine has no reaction in the Hisberg reaction. It is a colorless to light yellow transparent liquid with a strong ammonia odor and a slight smoke in the air. Boiling point: 89.5℃, relative density (water = 1): 0.70, relative density (air = 1): 3.48, slightly soluble in water, soluble in ethanol and ether. The aqueous solution is alkaline. It is flammable, and its vapor can form an explosive mixture with air, with an explosion limit of 1.2% to 8.0%. It is toxic and highly irritating.



Triethylamine Chemical Properties

Melting point 

-115 °C

Boiling point 

90 °C

density 

0.728

vapor density 

3.5 (vs air)

vapor pressure 

51.75 mm Hg ( 20 °C)

refractive index 

n20/D 1.401(lit.)

FEMA 

4246 | TRIETHYLAMINE

Fp 

20 °F

storage temp. 

Store below +30°C.

solubility 

water: soluble112g/L at 20°C

pka

10.75(at 25℃)

form 

Liquid

Specific Gravity

0.725 (20/4℃)

color 

Clear

PH

12.7 (100g/l, H2O, 15℃)(IUCLID)

Relative polarity

1.8

Odor

Strong ammonia-like odor

Odor Type

fishy

Odor Threshold

0.0054ppm

explosive limit

1.2-9.3%(V)

Water Solubility 

133 g/L (20 ºC)

Merck 

14,9666

JECFA Number

1611

BRN 

1843166

Henry's Law Constant

1.79 at 25 °C (Christie and Crisp, 1967)

Exposure limits

NIOSH REL: IDLH 200 ppm; OSHA PEL: TWA 25 ppm (100 mg/m3); ACGIH TLV: TWA 1 ppm, STEL 3 ppm (adopted).

Dielectric constant

5.0(Ambient)

Stability:

Stable. Extremely flammable. Readily forms explosive mixtures with air. Note low flash point. Incompatible with strong oxidizing agents, strong acids, ketones, aldehydes, halogenated hydrocarbons.

InChIKey

ZMANZCXQSJIPKH-UHFFFAOYSA-N

LogP

1.65

CAS DataBase Reference

121-44-8(CAS DataBase Reference)

NIST Chemistry Reference

Triethylamine(121-44-8)

EPA Substance Registry System

Triethylamine (121-44-8)

Safety Information

Hazard Codes 

F,C

Risk Statements 

11-20/21/22-35

Safety Statements 

3-16-26-29-36/37/39-45-61

RIDADR 

UN 1296 3/PG 2

WGK Germany 

1

RTECS 

YE0175000

34

Autoignition Temperature

593 °F

Hazard Note 

Highly Flammable/Corrosive

TSCA 

Yes

HazardClass 

3

PackingGroup 

II

HS Code 

29211910

Hazardous Substances Data

121-44-8(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 0.46 g/kg (Smyth)

IDLA

200 ppm


Product Application of Triethylamine CAS#121-44-8 

1. Triethylamine can be used as a solvent and raw material in the organic synthesis industry. It can be used to prepare catalysts for phosgene-based polycarbonate, inhibitors for tetrafluoroethylene, rubber vulcanization accelerators, special solvents in paint strippers, enamel anti-hardening agents, surfactants, preservatives, bactericides, ion exchange resins, dyes, fragrances, drugs, high-energy fuels and liquid rocket propellants, etc. Products that consume triethylamine in the pharmaceutical industry include (consumption quota, t/t): ampicillin sodium (0.465), amoxicillin (0.391), Pioneer IV (2.550), cefazolin sodium (2.442), cefradine (1.093), piperacillin (0.584), ketoconazole (8.00), vitamin B6 (0.502), fluoxic acid (Chemicalbook 10.00), praziquantel (0.667), thiotepa (1.970), penicillamine (1.290), berberine hydrochloride (0.030), isoprenaline (0.540), alprazolam (3.950), o-chlorophenylacetic acid (0.010) and pipemidic acid, etc.

2. Used in the preparation of quaternary amine compounds and the synthesis of catalysts, and also used as rubber vulcanization accelerators, penetrants and waterproofing agents;

3. Manufacture of quaternary ammonium compounds, synthesis of catalysts, rubber vulcanization accelerators, and photographers. Mobile phase modifier, used for separation of acidic, alkaline and neutral drugs by reverse phase high performance liquid chromatography (RP-HPLC).

4. Improve the separation of amino acids and amino acid amides by suppressing tailing. Used in the manufacture of medicines, pesticides, inhibitors, high energy fuels, rubber vulcanizers, etc.


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