Aminobutyric Acid CAS#56-12-2

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Chemical Name:Aminobutyric Acid

CAS No.:56-12-2

Molecular Formula: C4H9NO2

Molecular weight: 103.12

Sample: Available

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Product Details

Products Description of Aminobutyric Acid CAS#56-12-2

It is used in biochemical research and medicinally to treat various diseases caused by hepatic coma and cerebrovascular disorders. Pharmaceutical intermediates. 4-Aminobutyric acid has the effect of lowering blood lipids and is suitable for the treatment and prevention of various types of hepatic coma. It can treat poliomyelitis, cerebral hemorrhage, and can be used as an antidote for gas poisoning. Also used in biochemical research and organic synthesis. It can reduce blood ammonia and promote brain metabolism. It is used to treat various types of hepatic coma, as well as coma caused by stroke sequelae, cerebral arteriosclerosis, head trauma sequelae, uremia, gas poisoning, etc. Major inhibitory neurotransmitter in the brain; agonist of GABAA and GABAB receptors; increases Cl− conductivity.


Product Parameters of Aminobutyric Acid CAS#56-12-2

1. Names and Identifiers

Name

4-Aminobutyric acid

Synonyms

 

4-Aminobutanoic acid                  Butanoic acid, 4-amino-

EINECS 200-258-6                      GABA

g-Aminobutyric acid                    g-Amino-n-butyric Acid

gamma-aminobutyric acid              MFCD00008226

Г-Amino-n-butyric acid

 

CAS

 

No.56-12-2

 

CID

119

 

EINECS(EC#)

200-258-6

Molecular Formula

C4H9NO2 (isomer)

 

Inchi

InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)

 

InChIkey

 

BTCSSZJGUNDROE-UHFFFAOYSA-N

 

Canonical Smiles

 

C(CC(=O)O)CN

 

Isomers Smiles

 

C(CC(=O)O)CN

 

2.Properties

Density

 

1.2300 (estimate)

 

Melting point

 

195?°C (dec.)(lit.)

 

Boiling point

248oC at 760 mmHg

Refractive index

1.4650 (estimate)

 

Flash Point

 

103.8oC

Vapour Pressure

 

0.0±1.0 mmHg at 25°C

Precise Quality

 

103.06300

 

PSA

 

63.32000

 

logP

 

0.51020

Solubility

H2O: 1?M at?20?°C, clear, colorless

Appearance

 

H2O: 1?M at?20?°C, clear, colorless

Storage

Ambient temperatures.

 

Chemical Properties

White, powdery solid; savory, meat-like aroma

 

Color/Form

 

White to almost white

 

pKa

 

4.031(at 25℃)

 

Water Solubility

 

H2O: 1?M at?20?°C, clear, colorless | SOLUBLE

Stability

Stable under normal temperatures and pressures.

 

StorageTemp

 

Store at RT.




3. Use and Manufacturing

3.1 History

4-Aminobutyric acid (GABA) was first synthesized in 1883, and was first known only as a plant and microbe metabolic product. In 1950, however, GABA was discovered to be an integral part of the mammalian central nervous system.

3.2 Purification Methods

Crystallise GABA from aqueous EtOH or MeOH/Et2O. Also crystallise it by dissolving it in the least volume of H2O and adding 5-7 volumes of absolute EtOH. [Sherman Biochemical Preparations 4 91 1955, de Witt Org Synth Coll Vol II 25 1943, Beilstein 4 III 1316, 4 IV 2600.]

 

4. Safety and Handling

4.1 Hazard Codes

Xi,Xn

4.1 Risk Statements

36/37/38-20/21/22

4.1 Safety Statements

26-36

4.1 RIDADR

NONH for all modes of transport

4.1 WGK Germany

4.1 RTECS

ES6300000

4.1 Report

Reported in EPA TSCA Inventory.



Product Application of Aminobutyric Acid CAS#56-12-2

Pharmaceutical intermediates. 4-Aminobutyric acid has the effect of lowering blood lipids and is suitable for the treatment and prevention of various types of hepatic coma. It can treat poliomyelitis, cerebral hemorrhage, and can be used as an antidote for gas poisoning. Also used in biochemical research and organic synthesis.

It can reduce blood ammonia and promote brain metabolism. It is used to treat various types of hepatic coma, as well as coma caused by stroke sequelae, cerebral arteriosclerosis, head trauma sequelae, uremia, gas poisoning, etc.

Major inhibitory neurotransmitter in the brain; agonist of GABAA and GABAB receptors; increases Cl− conductivity.

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