Aminobutyric Acid CAS#56-12-2
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Chemical Name:Aminobutyric Acid
CAS No.:56-12-2
Molecular Formula: C4H9NO2
Molecular weight: 103.12
Sample: Available
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Products Description of Aminobutyric Acid CAS#56-12-2
It is used in biochemical research and medicinally to treat various diseases caused by hepatic coma and cerebrovascular disorders. Pharmaceutical intermediates. 4-Aminobutyric acid has the effect of lowering blood lipids and is suitable for the treatment and prevention of various types of hepatic coma. It can treat poliomyelitis, cerebral hemorrhage, and can be used as an antidote for gas poisoning. Also used in biochemical research and organic synthesis. It can reduce blood ammonia and promote brain metabolism. It is used to treat various types of hepatic coma, as well as coma caused by stroke sequelae, cerebral arteriosclerosis, head trauma sequelae, uremia, gas poisoning, etc. Major inhibitory neurotransmitter in the brain; agonist of GABAA and GABAB receptors; increases Cl− conductivity.
Product Parameters of Aminobutyric Acid CAS#56-12-2
1. Names and Identifiers
Name | 4-Aminobutyric acid |
Synonyms
| 4-Aminobutanoic acid Butanoic acid, 4-amino- EINECS 200-258-6 GABA g-Aminobutyric acid g-Amino-n-butyric Acid gamma-aminobutyric acid MFCD00008226 Г-Amino-n-butyric acid
|
CAS
| No.56-12-2
|
CID | 119
|
EINECS(EC#) | 200-258-6 |
Molecular Formula | C4H9NO2 (isomer)
|
Inchi | InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
|
InChIkey
| BTCSSZJGUNDROE-UHFFFAOYSA-N
|
Canonical Smiles
| C(CC(=O)O)CN
|
Isomers Smiles
| C(CC(=O)O)CN
|
2.Properties
Density
| 1.2300 (estimate)
|
Melting point
| 195?°C (dec.)(lit.)
|
Boiling point | 248oC at 760 mmHg |
Refractive index | 1.4650 (estimate)
|
Flash Point
| 103.8oC |
Vapour Pressure
| 0.0±1.0 mmHg at 25°C |
Precise Quality
| 103.06300
|
PSA
| 63.32000
|
logP
| 0.51020 |
Solubility | H2O: 1?M at?20?°C, clear, colorless |
Appearance
| H2O: 1?M at?20?°C, clear, colorless |
Storage | Ambient temperatures.
|
Chemical Properties | White, powdery solid; savory, meat-like aroma
|
Color/Form
| White to almost white
|
pKa
| 4.031(at 25℃)
|
Water Solubility
| H2O: 1?M at?20?°C, clear, colorless | SOLUBLE |
Stability | Stable under normal temperatures and pressures.
|
StorageTemp
| Store at RT. |
3. Use and Manufacturing
3.1 History
4-Aminobutyric acid (GABA) was first synthesized in 1883, and was first known only as a plant and microbe metabolic product. In 1950, however, GABA was discovered to be an integral part of the mammalian central nervous system.
3.2 Purification Methods
Crystallise GABA from aqueous EtOH or MeOH/Et2O. Also crystallise it by dissolving it in the least volume of H2O and adding 5-7 volumes of absolute EtOH. [Sherman Biochemical Preparations 4 91 1955, de Witt Org Synth Coll Vol II 25 1943, Beilstein 4 III 1316, 4 IV 2600.]
4. Safety and Handling
4.1 Hazard Codes
Xi,Xn
4.1 Risk Statements
36/37/38-20/21/22
4.1 Safety Statements
26-36
4.1 RIDADR
NONH for all modes of transport
4.1 WGK Germany
4.1 RTECS
ES6300000
4.1 Report
Reported in EPA TSCA Inventory.
Product Application of Aminobutyric Acid CAS#56-12-2
Pharmaceutical intermediates. 4-Aminobutyric acid has the effect of lowering blood lipids and is suitable for the treatment and prevention of various types of hepatic coma. It can treat poliomyelitis, cerebral hemorrhage, and can be used as an antidote for gas poisoning. Also used in biochemical research and organic synthesis.
It can reduce blood ammonia and promote brain metabolism. It is used to treat various types of hepatic coma, as well as coma caused by stroke sequelae, cerebral arteriosclerosis, head trauma sequelae, uremia, gas poisoning, etc.
Major inhibitory neurotransmitter in the brain; agonist of GABAA and GABAB receptors; increases Cl− conductivity.
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